Pharmaceutical Industry
Organic solvent-containing pharmaceutical materials, active pharmaceutical ingredients and pharmaceutical intermediates.
Closed-Loop Fluidized Bed Dryer
Closed-Loop Fluid Bed Dryer with Solvent Recovery
Designed for low-oxygen drying of solvent-containing materials with nitrogen recirculation and solvent recovery. Designed and manufactured for solvent-containing and oxygen-sensitive materials requiring enclosed fluidized drying in pharmaceutical applications. Review the working principle, performance features and available configuration details below when specifying your industrial project.
- Closed nitrogen circulation supports low-oxygen drying of organic-solvent feeds.
- Condensation recovers evaporated solvent for collection and potential reuse.
- Online oxygen, pressure and nitrogen-supply monitoring support process interlocking.
- Drying Medium
- Nitrogen
- System
- Closed-loop circulation
- Main Function
- Drying + solvent recovery
- Atmosphere
- Low oxygen
Product Essentials
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Technical Specifications
Process and configuration data
Listed values apply to the identified configuration. Confirm material conditions, utilities and optional equipment before selection.
| Parameter / Vessel volume (L) | 11 | 38 | 120 | 340 | 450 | 670 | 1000 | 1700 |
|---|---|---|---|---|---|---|---|---|
| Total vessel volume (L) | 11 | 38 | 120 | 340 | 450 | 670 | 1000 | 1700 |
| Vessel diameter (mm) | Ø400 | Ø600 | Ø800 | Ø1100 | Ø1300 | Ø1500 | Ø1600 | Ø1800 |
| Capacity (kg/batch) | 3–5 | 5–10 | 18–30 | 40–60 | 80–120 | 150–200 | 250–300 | 350–500 |
| Closed-loop fan power (kW) | 4.0 | 5.5 | 11 | 15 | 18.5 | 30 | 45 | 55 |
| Steam pressure (MPa) | 0.2–0.4 | — | — | — | — | — | — | — |
| Steam consumption (kg/h) | 15 | 35 | 70 | 120 | 190 | 220 | 330 | 445 |
| Compressed air consumption (m³/min) | 0.3 | 0.4 | 0.5 | 0.6 | 0.8 | 1.0 | 1.0 | 1.5 |
| Compressed air pressure (MPa) | 0.4–0.6 | — | — | — | — | — | — | — |
| Nitrogen pressure (MPa) | 0.4–0.6 | — | — | — | — | — | — | — |
| Nitrogen consumption (m³/min) | 0.15 | 0.20 | 0.25 | 0.30 | 0.35 | 0.40 | 0.50 | 0.70 |
| Coolant pressure (MPa) | 0.2–0.4 | — | — | — | — | — | — | — |
| Circulating coolant consumption (t/h) | 3.5 | 5.5 | 7.5 | 12.5 | 14.5 | 20 | 28 | 40 |
A dash indicates that no value is listed for that size in the supplied data. Pressure values retain their original column positions; other sizes require confirmation. Capacity is a reference batch range.
Recovery rate, capacity and utility consumption are reference values. Final equipment selection must be confirmed against the solvent system, feed properties and project safety requirements.
Applications
Solvent-containing and oxygen-sensitive materials requiring enclosed fluidized drying.
Applications include solvent-containing and oxygen-sensitive materials requiring enclosed fluidized drying in pharmaceutical applications. Confirm material properties and process conditions before selecting the equipment configuration.
Biochemical Industry
Biochemical materials requiring controlled-atmosphere drying and solvent handling.
Chemical Industry
Organic solvent-containing chemical products and fine chemicals.
Biological Industry
Biological materials requiring low-oxygen drying conditions.
Suitable Material Characteristics
Granules, powders, wet mixed particles, solvent-containing materials and oxygen-sensitive materials.
Working Principle
Nitrogen-protected fluidized drying with dust separation and solvent recovery.
The sealed process circulates nitrogen through heating, fluidization, filtration, condensation, dehumidification and reheating.
System Sealing & Air Removal
The system is sealed and the exhaust route removes internal air until the required oxygen concentration can be established.
Nitrogen Purging
Nitrogen is introduced through the controlled supply system. Make-up is adjusted automatically when the target low-oxygen condition is reached.
Nitrogen Heating
The circulation fan moves nitrogen through the heater before the conditioned gas enters the fluidized drying chamber.
Closed-Loop Fluidized Drying
Hot nitrogen passes through the material support plate, fluidizes the material and evaporates moisture and organic solvents.
Dust Separation
Fine particles entrained in the circulating gas are removed by the pulse-cleaned filtration system.
Solvent Condensation
Solvent-bearing gas enters the condenser, where vapor is cooled into liquid for collection and potential reuse.
Nitrogen Dehumidification
After condensation, the circulating gas is conditioned to remove recovered vapor and residual moisture.
Gas Reheating & Recycling
The dry nitrogen returns to the heater and continues through the closed-loop drying cycle.
Key Features
Closed nitrogen circulation for solvent recovery and controlled fluidized drying.
Performance depends on the selected solvent, material properties, batch loading and confirmed process conditions.
Efficient Solvent Recovery
Condensation recovers evaporated organic solvent, reducing solvent loss and process emissions.
Safe Inert Atmosphere Operation
Nitrogen circulation maintains a low-oxygen drying environment for suitable flammable or oxygen-sensitive materials.
Reduced Exhaust Heat Loss
Recycling conditioned nitrogen limits continuous hot-gas discharge compared with an open exhaust route.
Controlled Fluidized Drying
Positive-pressure hot nitrogen passes through the material support plate to provide direct gas-particle contact with reduced airflow requirements.
Pulse-Cleaned Dust Filtration
Selected filter media provide a smooth surface, large filtration area, high collection efficiency and low resistance to reduce powder adhesion.
Flexible Process Duty
The system can be configured for solvent-containing material drying, solvent recovery, combined drying and cooling duties.
Safety & Process Control
Monitoring and protection for the enclosed nitrogen circuit.
Final interlocks and explosion-protection measures are configured according to the solvent, site classification and applicable project requirements.
Online Oxygen Monitoring
The system continuously monitors oxygen concentration and activates nitrogen make-up when the preset value is exceeded.
Pressure Protection
Internal pressure is monitored continuously. The pressure-relief system operates when the configured limit is exceeded.
Nitrogen Supply Control
The control system monitors nitrogen supply condition and adjusts replenishment during purging and drying.
Explosion Protection
Explosion-protection measures are integrated according to solvent hazards, electrical requirements and project safety review.
Dust Control
Pulse back-blowing maintains filter performance and limits fine-powder accumulation in the circulating gas route.
Condensate Collection
Recovered liquid solvent is separated from the gas loop and directed to the configured collection system.
Selection Support
Information required for dryer equipment selection.
Provide the following material, solvent, production, utility and safety data for preliminary model evaluation.
Material nameSolvent typeSolvent contentBatch capacityInitial moisture contentRequired final moistureRequired solvent recovery rateOxygen sensitivityHeat sensitivityRequired production capacityAvailable steam supplyNitrogen supply conditionsExplosion protection requirementsAutomation requirements
